Keith D. Paulsen;Venkataramanan Krishnaswamy;Pilar Beatriz Garcia Allende;Olga Maria Conde;José Miguel Lopez-Higuera;Brian William Pogue
发明人:
Brian William Pogue,Venkataramanan Krishnaswamy,Keith D. Paulsen,Pilar Beatriz Garcia Allende,Olga Maria Conde,José Miguel Lopez-Higuera
申请号：
US13140748
公开号：
US20130338479A1
申请日:
2009.12.18
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A method and apparatus is described for optically scanning a field of view, the field of view including at least part of an organ as exposed during surgery, and for identifying and classifying areas of tumor within the field of view. The apparatus obtains a spectrum at each pixel of the field of view, and classifies pixels with a kNN-type or neural network classifier previously trained on samples of tumor and organ classified by a pathologist. Embodiments use statistical parameters extracted from each pixel and neighboring pixels. Results are displayed as a color-encoded map of tissue types to the surgeon. In variations, the apparatus provides light at one or more fluorescence stimulus wavelengths and measures the fluorescence light spectrum emitted from tissue corresponding to each stimulus wavelength. The measured emitted fluorescence light spectra are further used by the classifier to identify tissue types in the field of view.
