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MANGANESE COMPLEXES WITH SUBSTITUTED BISPHOSPHONATES USEFUL AS IMAGING AND THERAPEUTIC AGENTS
专利权人:
DUKE UNIVERSITY
发明人:
LASCOLA, CHRISTOPHER DAVID
申请号:
CA3021425
公开号:
CA3021425A1
申请日:
2016.10.26
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Provided herein is a compound useful as a magnetic resonance imaging (MRI) contrast agent and a therapeutic agent, said compound having a structure represented by: Y X Z wherein, X is Mn(II), and Y and Z are each independently a bisphosphonate coupled to one or more therapeutic agents. Methods of use of the compound for MRI imaging and treatment for cancer or a microbial infection are also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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