Ståle Petter Lyngstadaas;Christiane Petzold;Jan Erik Ellingsen;Marta Monjo
发明人:
Ståle Petter Lyngstadaas,Marta Monjo,Christiane Petzold,Jan Erik Ellingsen
申请号：
US13558971
公开号：
US08821568B2
申请日:
2012.07.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
An implant to be used as medical or dental implant, comprising a metallic or polymeric base which is covered by the vitamin D precursor cholecalciferol. The implant can be obtained by direct covering of the polymeric or metallic base with a solution comprising cholecalciferol or also covering the base with the 7-dehydrocholesterol (7-DHC), and subsequently irradiated with UV light to induce the formation of cholecalciferol. Optionally, the coating of the implant may include an antioxidant such as vitamin E. This implant enhances osseointegration in compromised patients by means of the endogenous synthesis and activity of vitamin D in hard and mineralized tissue regeneration. Furthermore, a method to obtain these implants which comprises coating the surface of the implant directly with cholecalciferol or with a specific concentration of 7-DHC and irradiated with UV light to induce the formation of cholecalciferol.
