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Compositions and methods for nucleic acid expression and protein secretion in bacteroides
专利权人:
The Board of Trustees of the Leland Stanford Junior University
发明人:
Sonnenburg, Justin L.,Whitaker, Weston R.,Stanley, Elizabeth
申请号:
AU2017252409
公开号:
AU2017252409A1
申请日:
2017.04.18
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
Provided are nucleic acids that include a promoter, where the promoter is operable in a Bacteroides cell and is operably linked to a heterologous nucleotide sequence of interest. Also provided are nucleic acids that include a promoter (operable in a prokaryotic cell such as a Bacteroides cell) operably linked to a sequence encoding a synthetic ribosomal binding site (RBS). Also provided are fusion proteins (and nucleic acids encoding them) in which a secreted Bacteroides polypeptide is fused to a heterologous polypeptide of interest. Also provided are prokaryotic cells
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