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LUTEINIZING HORMONE LIQUID FORMULATIONS
专利权人:
MERCK SERONO S.A
发明人:
AGOSTINETTO, RITA,SAMARITANI, FABRIZIO,DEL RIO, ALESSANDRA,RICHARD, JOEL
申请号:
NZ58399108
公开号:
NZ583991A
申请日:
2008.10.29
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a liquid formulation containing luteinizing hormone (LH) or a variant thereof characterized in that said formulation comprises a phosphate buffer and a stabilizing amount of arginine or salts thereof at a concentration of at or about 10 to at or about 50 mg/ml and/or lysine or salts thereof at a concentration of at or about 10 to at or about 50 mg/ml. Use of the formulation in a medicament for treatment of infertility and the use in combination with follicle-stimulating hormone (FSH) is also disclosed.
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