A pharmaceutical composition for the prevention, relief and / or treatment of epileptic seizures, comprising (a) lacosamide, or a pharmaceutically acceptable salt thereof, and (b) an additional compound for prevention, relief and / or the treatment of epileptic seizures, optionally together with a pharmaceutically acceptable carrier, diluent and / or adjuvant, wherein the additional compound (b) is selected from lamotrigine, brivaracetam, topiramate, gabapentin and levetiracetam, where (i) lamotrigine and lacosamide are present in the composition in a fixed proportion of lamotrigine: lacosamide from 1: 3 to 3: 1, (ii) brivaracetam and lacosamide are present in the composition in a fixed proportion of brivaracetam: lacosamide from 1: 3 to 6 : 1, (iii) topiramate and lacosamide are present in the composition in a fixed proportion of topiramate: lacosamide from 1: 1 to 6: 1, (iv) gabapentin and lacosamide are present in the composition in a fixed ratio of gabapentin: lacosamide from 1: 1 to 3: 1, or (v) levetiracetam and lacosamide are present in the composition in a fixed proportion of levetiracetam: lacosamide from 1: 3 to 6: 1 where the proportions of Fixed doses are calculated on the ED50 values of the individual compounds (a) and (b), and where (a) lacosamide and compound (b) can be formulated in a unit dosage form or can be formulated in separate dosage, separate dosage forms that can be administered simultaneously and / or subsequently, and packaged together or presented together in separate packages.Una composición farmacéutica para la prevención, el alivio y/o el tratamiento de ataques epilépticos, que comprende (a) lacosamida, o una sal de la misma farmacéuticamente aceptable, y (b) un compuesto adicional para la prevención, el alivio y/o el tratamiento de ataques epilépticos, opcionalmente junto con un vehículo, diluyente y/o adyuvante farmacéuticamente aceptable, en donde el compuesto adicional (b) se selecciona de lamotrigina, brivaracetam, topiramato, gab
