Matthew David Butts,Robert Edgar Colborn,Peter John Bonitatibus, Jr.,Andrew Soliz Torres,Brian Christopher Bales,Michael Ernest Marino,Bruce Allan Hay,Amit Mohan Kulkarni
申请号：
US13872539
公开号：
US09399075B2
申请日:
2013.04.29
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compositions of nanoparticles functionalized with at least one zwitterionic moiety, methods for making a plurality of nanoparticles, and methods of their use as diagnostic agents are provided. The nanoparticles have characteristics that result in minimal retention of the particles in the body compared to other nanoparticles. The nanoparticle comprising a nanoparticulate transition metal oxide covalently functionalized with a silane-functionalized non-targeting zwitterionic moiety.
