Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies

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专利权人:

Intrexon Corporation

发明人:

Patel, Dimki S.,Patel, Amit N.

申请号：

AU2016353342

公开号：

AU2016353342A1

申请日:

2016.11.11

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

The present invention provides compositions and methods useful for treating disorders amenable to therapy via introduction of multigenic expression vectors. More particularly, the invention provides vectors and polynucleotides encoding polypeptides for treatment of cardiac disorders wherein said polypeptides may comprise a cytokine, a chemokine, and/or an angiogenic polypeptide, or functional derivatives thereof. Also provided, as compositions of the invention, are linkers useful for connecting and expressing functional (biologically active) polypeptides from single, multigenic-expression constructs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/