Described is a medicament delivery device comprising a body (1) adapted to accommodate a cartridge (2) containing a medicament (3), and a reservoir (7, 17) coupled to the body (1), the reservoir (7, 17) containing a fluid (13) and a plunger (8, 18). The cartridge (2) is axially movable relative to the body (1) between a retracted position and an extended position. Axial movement of the cartridge (2) from the retracted position to the extended position moves the plunger (8, 18) to expel the fluid (13) from the reservoir (7, 17).