A personal care composition comprising a methyl naphthalenyl ketone or a derivative thereof, such as 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2naphthalenyl)-ethan-1-one, for down regulating at least one TRP receptor associated with a pain response, including but not limited to TRPV1 and TRPA1 receptors to reduce skin irritation associated with hair removal.限定ではないがTRPV1及びTRPA1受容体を含む、疼痛反応に関連する少なくとも1つのTRP受容体をダウンレギュレーションして、脱毛に関連する皮膚刺激を低減させるために1-(1,2,3,4,5,6,7,8-オクタヒドロ-2,3,8,8-テトラメチル-2ナフタレニル)-エタン-1-オンなどのメチルナフタレニルケトン又はその誘導体を含む、パーソナルケア組成物。