ELMORE, Steven,SOUERS, Andrew,WANG, Li Chun,GHAYUR, Tariq,PERPER, Stuart J.
申请号:
PH12016500939
公开号:
PH12016500939B1
申请日:
2016.05.20
申请国别(地区):
PH
年份:
2017
代理人:
摘要:
This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogrens Syndrome with compounds that selectively inhibit the activity of Bcl 2 anti apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl- xL.