Rene Amstutz,Guido Bold,Simona Cotesta,Wolfgang Jahnke,Andreas Marzinzik,Juliane Constanze Desiree Hartwieg,Silvio Ofner,Frédérik Stauffer,Johann Zimmermann,AMSTUTZ, René ,BOLD, Guido ,COTESTA, Simona ,JAHNKE, Wolfgang ,MARZINZIK, Andreas ,MUELLER-HARTWIEG, Constanze ,OFNER, Silvio ,STAUFFER, Frédéric ,ZIMMERMANN, Johann
申请号:
US12918880
公开号:
US20120094958A1
申请日:
2009.02.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention relates to a compound of formula (I) wherein the substituents are as described in the specification, which are useful as farnesyl pyrophosphate synthase modulators, e.g. in the treatment of proliferative diseases, to methods of manufacturing such compounds and to intermediates thereof.