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EDIBLE ORAL STRIP OR WAFER DOSAGE FORM CONTAINING ION EXCHANGE RESIN FOR TASTE MASKING
专利权人:
LTS LOHMANN THERAPIE-SYSTEME AG
发明人:
LI, MICHAEL HSIN CHWEN,KRUMME, MARKUS
申请号:
CA2838589
公开号:
CA2838589A1
申请日:
2012.05.30
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
An edible oral film strip dosage form containing an unpalatable acidic active pharmaceutical ingredient, particularly ketoprofen, and an ion exchange resin as a primary taste masking agent, along with an optional alkaline agent and further optionally containing one or more secondary taste masking agents is provided. The edible oral film strip dosage matrix is formed from at least one water soluble or miscible polymer(s). The optional secondary taste masking ingredients include one or more of flavoring agent(s), sweetener(s), cooling sensation agent(s), and taste receptor blocker(s). The inventive dosages minimize or completely mask the bitterness, burning sensation and throat irritation associated with many acidic active pharmaceutical ingredients. Methods for preparing the inventive edible oral film strip dosage forms are disclosed, as well as their method of administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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