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Lincosamide derivative and antibacterial agent comprising the same
专利权人:
Seikaファルマ株式会社;Meiji;Meiji Seikaファルマ株式会社
发明人:
梅村 英二郎,久村 興,真崎 里美,上田 和孝,脇山 佳也,佐藤 康夫,山本 幹夫,味戸 慶一,渡邊 尚志,梶 千津子
申请号:
JP2009516374
公开号:
JP5290166B2
申请日:
2008.05.30
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
An objective of the present invention is to provide compounds of formula (I) or their pharmacologically acceptable salts or solvates wherein A represents aryl while R 1 represents a five- or six-membered monocyclic heterocyclic group, or A represents a four- to six-membered monocyclic heterocyclic group while R 1 represents aryl or a five- or six-membered monocyclic heterocyclic group; R 2 represents a hydrogen atom or C 1-6 alkyl; R 3 represents C 1-6 alkyl or C 3-6 cycloalkyl-C 1-4 alkyl; R 4 , R 5 , and R 6 represent a hydrogen atom; R 7 represents C 1-6 alkyl; and m is 1 to 3. The compounds are novel lincosamide derivatives that have a potent activity against resistant Streptococcus pneumoniae. Further, the compounds are usable as antimicrobial agents and are useful for preventing or treating bacterial infectious diseases.
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来源网址:
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