Epsilon toxin epitopes from clostridium perfringens with reduced toxicity

• 收藏
• 分享

专利权人:

University of Exeter

发明人:

Titball, Richard W.,Bokori-Brown, Monika,Naylor, Claire

申请号：

AU2013239465

公开号：

AU2013239465A1

申请日:

2013.03.28

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

There is provided an epsilon toxin epitope polypeptide comprising a sequence of at least 10 contiguous amino acids from SEQ ID NO:3, the sequence comprising a mutation of at least one tyrosine residue compared to the equivalent sequence in SEQ ID NO:3, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:5 and having reduced toxicity compared with the toxicity of SEQ ID NO:5. The polypeptide is useful in a method of vaccinating a subject against developing a disease caused by

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/