MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE

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专利权人:

JUDD, Andrew;BRAJE, Wilfried;ABBVIE INC.;KUNZER, Aaron;DOHERTY, George;TAO,;JANTOS, Katja;SONG, Xiaohong;SOUERS, Andrew;MASTRACCHIO, Anthony;JI, Cheng;SULLIVAN, Gerard;ABBVIE DEUTSCHLAND GMBH & CO. KG

发明人:

BRAJE, Wilfried,DOHERTY, George,JANTOS, Katja,JI, Cheng,JUDD, Andrew,KUNZER, Aaron,MASTRACCHIO, Anthony,SONG, Xiaohong,SOUERS, Andrew,SULLIVAN, Gerard,TAO, Zhi-Fu,TESKE, Jesse,WANG, Xilu,WENDT, Michae

申请号：

SG11202001182Q

公开号：

SG11202001182QA

申请日:

2018.08.15

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

wherein A2, A3, A4, A6, A7, A8, R15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of formula (I).

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