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Lutzomyia longipalpis polypeptides and methods of use
专利权人:
The United States of America as represented by the Secretary of the Department of Health and Human Services;Fundacao Oswaldo Cruz (FIOCRUZ)
发明人:
Jesus G. Valenzuela,Jose M. C. Ribeiro,Aldina Barral,Manoel Barral Netto,Claudia I. Brodskyn,Regis Gomes
申请号:
US14802168
公开号:
US09382302B2
申请日:
2015.07.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Substantially purified salivary Lu. longipalpis polypeptides, and polynucleotides encoding these polypeptides are disclosed. Vectors and host cells including the Lu. longipalpis polynucleotides are also disclosed. In one embodiment, a method is disclosed for inducing an immune response to sand fly saliva. In other embodiments, methods for treating, diagnosing, or preventing Leishmaniasis are disclosed.
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