Peripheral catheters having diffusion holes can be reinforced by embedding stripe material within the material of the catheter tube body. The stripe material can be embedded using a coextrusion process. The stripe material may consist of one or more stripes which may be arranged in a straight or non-linear pattern such as a helical pattern. The diffusion holes can be positioned between adjacent stripes or between adjacent portions of a single stripe. The diffusion holes can be formed after the stripe material has been embedded. A lubricant may be applied to a peripheral catheter that includes stripe material and diffusion holes.