The present invention pertains to a bisoprolol-containing patch preparation containing a support body and an adhesive layer laminated to one surface of the support body and containing an adhesive agent and free bisoprolol, the stress relaxation percentage of the adhesive layer being 20-90%, and the shear stress of the adhesive layer being 1.0-6.5 N/30 mm width. The bisoprolol-containing patch preparation has suppressed peeling during use, has superior skin adhesiveness, and suppresses skin irritation during delamination. As the adhesive agent, a rubber-based adhesive is preferable, and a polyisobutylene and/or styrene-isoprene-styrene block copolymer is more preferable.本發明相關的含畢索普洛之貼附製劑,係包括有:支撐體;以及積層於上述支撐體的單面上且含有游離型畢索普洛與黏著劑的黏著劑層;其中,黏著劑層的應力緩和率係20~90%,且黏著劑層的剪切應力係1.0~6.5N/30mm寬。本發明的含畢索普洛之貼附製劑係可抑制使用中發生掀起,具有優異的皮膚接著性,且在剝離時能抑制皮膚刺激。黏著劑較佳係橡膠系黏著劑,更佳係聚異丁烯及/或苯乙烯-異戊二烯-苯乙烯嵌段共聚物。
