CHEN, JINGSONG,WOLFINBARGER, LLOYD,CHEN, SILVIA S.
申请号：
CA2733273
公开号：
CA2733273C
申请日:
2009.08.07
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention is directed to a process for making a tissue repair implanthaving a porous sponge-like structure torepair bone, cartilage, or soft tissue defects by producing a connectivetissue homogenate from one or more connective tissues,mixing the connective tissue homogenate with a carrier solution to produce aconnective tissue carrier, optionally mixing one ormore natural or synthetic bone fragments with said connective tissue carrierto produce a tissue repair mixture, freezing orfreeze--drying the tissue repair mixture to produce a porous sponge-likestructure and create a three-dimensional framework to entrap thenatural or synthetic bone fragments, treating the frozen or freeze-driedporous sponge-like structure with one or more treatmentsolutions to produce a stabilized porous sponge-like structure A crudelyfragmented connective tissue from one or more connectivetissues is optionally mixed with the tissue repair mixture before freezing orfreeze-drying.
