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METHOD OF CONSTRUCTING MASSES OF MYOCARDIAL CELLS AND USE OF THE MYOCARDIAL CELL MASS
专利权人:
DAIICHI SANKYO COMPANY, LIMITED;KEIO UNIVERSITY
发明人:
Fumiyuki HATTORI,Keiichi FUKUDA
申请号:
US14798650
公开号:
US20150366918A1
申请日:
2015.07.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The object of the present invention is to improve the post-transplantation engraftment rate of cardiomyocytes that have been purified to such an extent that they are free from non-cardiomyocytes and any components derived from other species.To solve this problem, the present inventors studied the possibility of constructing cell masses from the purified cardiomyocytes. As a result, they revealed that the stated problem could be solved by providing a method of preparing cell masses of cardiomyocytes derived from pluripotent stem cells, characterized in that cell masses of aggregated cells containing cardiomyocytes that had been differentiated and induced from pluripotent stern cells were dispersed to single cells to thereby obtain purified cardiomyocytes, which were then cultured in a culture medium under serum-free conditions so that they were reaggregated.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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