Alan Buckler;Jeffrey Hewett;Chantale T. Guy;Chao-Min Chen
发明人:
Alan Buckler,Chao-Min Chen,Chantale T. Guy,Jeffrey Hewett
申请号：
US13319133
公开号：
US20120183543A1
申请日:
2010.05.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides novel methods of inhibiting fibrosis, as well as methods of treating or inhibiting fibrotic disorders, using BMP9 and/or BMP10 antagonists. The present invention also provides methods of assessing whether a subject has or is at risk of developing a fibrotic disorder by detecting levels of BMP9 and/or BMP10. Further provided are methods of assessing the efficacy of a treatment regimen for treating a fibrotic disorder by detecting and comparing pre-treatment levels of BMP9 and BMP10 with post-treatment levels of BMP9 and BMP10.
