This invention is the medicine composition which includes the medicine of solubility in the neutral oil and the aforementioned oil, the aforementioned medicine offers the medicine composition for the hypoglossal medicine delivery which is not nitroglycerin. In addition, this invention offers the delivery instrument which is suited for the hypoglossal delivery of the aforementioned composition.本発明は、中性油及び前記油に可溶性の薬物を含む医薬組成物であり、前記薬物はニトログリセリンでない舌下薬物送達用の医薬組成物を提供する。また、本発明は、前記組成物の舌下送達に適した送達器具を提供する。