CHI, DAE YOON,LEE, BYOUNG SE,LEE, SANG JU,RYU, JIN-SOOK,OH, SEUNG JUN
申请号:
CA2810952
公开号:
CA2810952A1
申请日:
2011.09.06
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention generally relates to the preparation of 18F-!abeled radiopharmaceuticals. In particular, this invention relates to the advanced processes for an efficient eiution of [18F]fluoride trapped in a cartridge filled with quaternary ammonium polymer which comprises inert non-basic and non-nucleophilic counter anions. The said methods and polymer cartridges allow the rapid preparation of suitable [18F]fiuoride solution, which is also less basic to reduce the formation of byproducts, finally to increase radiochemical yield and purity of 18F-radiopharmaceuticals.