Solid cancer tissue targeting bacterium and use thereof

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专利权人:

INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY;전남대학교산학협력단

发明人:

MIN, JUNG JOON,민정준,PARK, SEUNG HWAN,박승환,CHOI, HYON EL,최현일,MIN, JUNG JOONKR,PARK, SEUNG HWANKR,CHOI, HYON ELKR

申请号：

KR1020150051085

公开号：

KR1020160121276A

申请日:

2015.04.10

申请国别(地区):

KR

年份:

2016

代理人:

摘要：

The present invention relates to cancer tissue targeting bacteria and, more specifically, to solid cancer tissue targeting bacteria and a use thereof. A composition for treating solid cancer comprises a Salmonella strain genetically engineered to represent a peptide, on the surface thereof, comprising a bacterial-derived RGD motif operably linked to a promoter, wherein integrin is overexpressed in the solid cancer.본 발명은 암조직 타겟팅 박테리아에 관한 것으로서, 더 상세하게는 고형암 조직 타겟팅 박테리아 및 그의 용도에 관한 것이다.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/