A patient monitoring system may receive a physiological signal such as a photoplethysmograph (PPG) signal that exhibits frequency and amplitude modulation based on respiration. A phase locked loop may generate a frequency demodulated signal and an amplitude demodulated signal from the PPG signal. An autocorrelation sequence may be generated for each of the frequency demodulated signal and the amplitude demodulated signal. The autocorrelation sequences may be combined and respiration information may be determined based on the combined autocorrelation sequence.
