TECHNISCHE UNIVERSITAT MUNCHEN - KLINIKUM RECHTS DER ISAR;TECHNISCHE UNIVERSITAT MUNCHEN
发明人:
WURZER, ALEXANDER JOSEF,WESTER, HANS-JURGEN,EIBER, MATTHIAS JOHANNES
申请号:
CA3071315
公开号:
CA3071315A1
申请日:
2018.07.30
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to a ligand-SIFA-chelator conjugate, comprising,within in a single molecule three separatemoieties:(a)one or more ligands which are capable of binding to a disease-relevant target molecule, (b)a silicon-fluoride acceptor (SIFA)moiety which comprises a covalent bond between a silicon atom and a fluorineatom, and(c)one or more chelating groups, optionallycontaining a chelated nonradioactive or radioactive cation.