FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNYJ TSENTR SERDECHNO-SOSUDISTOJ KHIRURGII IMENI A.N. BAKULEVA" ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK (FGBU "NTSSSKH IM.A.N.BAKULEVA" RAMN)
发明人:
BOKERIJA LEONID ANTONOVICH,Бокерия Леонид Антонович,GAVRILOV OLEG KONSTANTINOVICH,Гаврилов Олег Константинович,SOKOLSKAJA NADEZHDA OLEGOVNA,Сокольская Надежда Олеговна,SOKOLSKAJA MARIJA ALEKSANDROVNA
申请号:
RU2011136151/14
公开号:
RU0002476146C1
申请日:
2011.08.31
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to clinical diagnostics, and can be used as express-method of detecting impairment of blood aggregate state. For this purpose echcardiographic and electrocardiographic examinations are performed, systolic arterial pressure and body temperature are measured. Obtained data are processed and obtained characteristic is used to carry out comparison with control characteristic, preliminarily obtained after processing of data of echcardiographic and electrocardiographic examinations, measurement of systolic pressure, temperature in healthy blood donors. Results of comparison are used to judge about degree of impairment of blood aggregate state, as control characteristic used is digital characteristic of degree of hemoaggregation interaction in blood flow (HAWR), which is calculated by formula where Wng is potential energy of blood gravitation field Wng = -γ M Wne is potential energy of blood electric field Wne = LMT-3 Y-1 Wnc is potential energy of coagulation chemical interaction Wnc = Σ (ni×Eci) Wk is kinetic energy of blood flow Wk = MV2/2, M is weight of circulating blood volume G is gravitational potential of earth, L is length of arterial section of blood flow Y is current intensity in volume conductor ni is number of bonds of molecules of blood cells Eci is average value of bond energies V is rate of blood flow in output part of left ventricle P is systolic arterial pressure T is absolute temperature. If HAWR>9.82, degree of impairment of aggregation potential is determined as hypercoagulation. If HAWR<9.64, impairment is determined as hypocoagulation. If HAWR is 9.64-9.82, it is determined as normal aggregate blood state.EFFECT: method makes it possible to determine degree of impairment of blood aggregate state in efficient non-invasive way.1 tbl, 4 exИзобретение относится к медицине, а именно к клинической диагностике, и может быть использовано как экспресс-метод выявления нарушений агрегатного сост