ABSTRACT - 596263 Disclosed herein is a composition comprising: (a) an aqueous lubricant base comprising a combination of lubricious agents in an aqueous balanced salt solution wherein the combination comprises methylparaben and one or more of: a glycerol, arabinogalactan, PACGH, dextran, polyacrylic acid, carbomer, polyethylene oxide, copolymers of ethylene oxide and propylene oxide, methylcellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropylmethyl cellulose, polyethylene glycol, propylene glycol, hydroxypropyl guar, or a plant oil； and (b) a viability-maintaining agent comprising a combination of calcium, sodium, potassium, and magnesium ions； wherein the composition is a lubricant composition formulated for vaginal use which excludes therapeutic drugs, has a pH in the range of 5.0-9.0, an osmolality in the range of 200 to 700 mOsm/kg, and kills less than about 1% of the spermatozoa that are exposed to the composition. This aqueous lubricant composition is suitable as a personal moisturizer and lubricant that relive vaginal dryness and may promote binding of sperm to eggs, and/or facilitate the process of fertilization of an oocyte.
