PROTÉINES DE FUSION CONTENANT DES ANTICORPS ANTI-CD47 ET DES CYTOKINES

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专利权人:

I-Mab Biopharma US Limited

发明人:

WANG, Zhengyi,CAO, Wei,FANG, Lei,GUO, Bingshi

申请号：

EP18875854

公开号：

EP3541941A4

申请日:

2018.11.12

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Provided are fusion proteins containing cytokines and novel CD47 antibodies or immunologically active fragments thereof, as well as pharmaceutical composition containing such fusion proteins that can be used for treatment of diseases mediated by CD47 or inhibition of phagocytosis or platelet aggregation. These fused proteins have low immunogenicity in humans and cause low or no level of red blood cell depletion or hemagglutination.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/