DURACK, GARY,HATCHER, JEREMY,WESTFALL, LON A.,HELBING, DAVID R.,WALLACE, JEFFREY D.,VANDRE, GARY P.,DIDION, BRADLEY,NAYAK, NIRAJ V.,ANZAR, MUHAMMAD,LUDWIG, CINDY L.,GRAHAM, JEFFREY A.,CROWLEY, KATHLEE
申请号:
ES09014407
公开号:
ES2524040T3
申请日:
2004.03.29
申请国别(地区):
ES
年份:
2014
代理人:
摘要:
A system flow cytometry to classify a mixture of particles comprises particles having an A and particles characteristic having a characteristic B, the system a fluid supply comprising for supplying a fluid containing the particles, an apparatus cytometric flow for the fluid, forming into a stream and use flow cytometry to sort the particles according to the characteristics, and a classification system for classifying particles according to the organization and according to a sorting strategy to provide at least one population It contains the desired particles, the improvement comprising: a control that responds to information received from the apparatus flow cytometry for: a) control the sorting system to vary its sorting strategy as a function of: (1) the purity of such or stocks in relation to the particles to the feature or characteristic B particles and (2) the amount of the particles to the feature or particles with B characteristic in said population or populations relative to the total amount of particles with characteristic A or particles B characteristic in the current and / or ( B) control the system fluid supply to vary the rate at which fluid is delivered as a function of the amount of particles having characteristic a or particles B characteristic in said population or populations relative to the total amount of particles with characteristic a or characteristic B particles in the stream.Un sistema de citometría de flujo para clasificar una mezcla de partículas que incluye partículas que tienen una característica A y partículas que tienen una característica B, comprendiendo el sistema un sistema de suministro de fluidos para suministrar un fluido que contiene las partículas, un aparato de citometría de flujo para recibir el fluido, conformarlo en una corriente y utilizar la citometría de flujo para organizar las partículas según las características, y un sistema de clasificación para clasificar las partículas según la organización y según una estrategia