Glucose sensor for implantation within a mammal, the analyte sensor comprising a flexible substrate, a conductive layer disposed on the substrate and comprising a reference electrode, a working electrode and a counter electrode. The sensor further comprises an analyte sensing layer, an analyte modulating layer and a cover layer disposed on the analyte sensor apparatus, wherein the cover layer comprises an aperture positioned on the cover layer so as to facilitate an analyte present in the mammal contacting and diffusing through the analyte modulating layer and contacting the analyte sensing layer. The device further comprises a processor for noise reduction and data processing A fuse element for avoiding overuse, circuitry for generating a pulsed sensing current and means for sensing if the sensor is sufficiently hydrated. Typical embodiments of the invention include glucose sensors used in the management of diabetes.Linvention fournit des capteurs danalyte ayant des éléments et/ou configurations déléments optimisés, de même que des procédés de fabrication et dutilisation de tels capteurs. Des modes de réalisation typiques de linvention comprennent des capteurs de glucose utilisés dans la gestion du diabète.
