3- [4- (7h-pyrrolo [2,3-d] pyrimidin-4-yl) -1h-pyrazol-1-yl] octane- or heptane-nitrile as jak inhibitors

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专利权人:

INCYTE CORPORATION

发明人:

JAMES D. RODGERS,YUN-LONG LI

申请号：

BRPI1012108

公开号：

BRPI1012108A2

申请日:

2010.05.21

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]heptanenitrile, as well as its compositions and methods of use, which is useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer, and other diseases.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/