THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE COMPRISING 2-AMINO-1,3-PROPANAEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE
A novel therapeutic and prophylactic agent for inflammatory bowel diseases and a method for treating inflammatory bowel diseases. The agent comprises a 2-amino-1,3-propanediol derivative ( e.g ., 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propanediol hydrochloride) represented by the chemical formula (1) or a pharmaceutically acceptable salt or hydrate thereof: The agent is useful in the treatment or prevention of Crohn's disease, Crohn's disease in large intestine, intestinal Behcet's disease, ulcerative colitis, bleeding rectal ulcer and pouchitis.로 표현되는 스핑고신-1-인산 수용체 작용제인 2-아미노-1,3-프로판디올유도체(구체예: 2-아미노-2-[4-(3-벤질옥시페닐티오)-2-클로로페닐]에틸-1,3-프로판디올의 염산염), 또는 약학적으로 허용되는 그 염 및 수화물은 염증성 장질환 크론병, 대장 크론병, 장관형 베체트병, 궤양성 대장염, 출혈성 직장 궤양 또는 회장낭염의 치료제 또는 예방제로서 유용한 것을 발견하였다.
