BEYER, Simon,MOHAMED, Tamer,PAN, Sheng,WADSWORTH, Sam
申请号：
EP16810681
公开号：
EP3310902A4
申请日:
2016.06.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided herein are synthetic living tissue structures comprising multiple layers of fibers deposited in solidified form from a 3D bioprinter, together with kits and methods of use related thereto. The fibers comprise a plurality of mammalian cells dispensed within a solidified biocompatible matrix. The structural integrity of the fiber is maintained upon and after deposition without any additional crosslinking. The fiber is continuously bioprinted through at least two layers of the structure. In one aspect, synthetic muscle tissue structures exhibit a readily assayable contractile functionality.
