Mayo Foundation for Medical Education and Research
发明人:
Candace Y. W. Lee,John C. Burnett, Jr.
申请号:
US15232429
公开号:
US09587004B2
申请日:
2016.08.09
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.