用於治療肌力退化症之肌肉生長抑制素(MYOSTATIN)或活化素(ACTIVIN)拮抗劑农业专利-农业学术服务平台

发明人:: KORTEBEIN, PATRICK,寇田宾　派屈克,寇田賓　派屈克,ROOKS, DANIEL,鲁克斯　丹尼尔,魯克斯　丹尼爾,KLICKSTEIN, LLOYD B.,克力克斯登　洛伊德Ｂ,ROUBENOFF, RONENN,罗宾欧夫　罗南,羅賓歐夫　羅南,GLASS, DAVID,葛拉斯　大卫,葛拉斯　大衛,TRIFILIEFF, ESTELLE,崔菲利夫　艾斯特拉,崔,寇田宾派屈克,寇田賓派屈克,鲁克斯丹尼尔,魯克斯丹尼爾,克力克斯登洛伊德B,罗宾欧夫罗南,羅賓歐夫羅南,葛拉斯大卫,葛拉斯大衛,崔菲利夫艾斯特拉

摘要：: The present invention relates to myostatin or activin antagonists, dose regimen and pharmaceutical compositions thereof, for the treatment of sarcopenia, in particular age-related sarcopenia. Especially, the myostatin or activin antagonist bimagrumab was found to be beneficial in the treatment of older adults with sarcopenia with respect to increasing their skeletal muscle strength and function.本發明係關於肌肉生長抑制素或活化素拮抗劑、其給藥方案及醫藥組合物，其用於治療肌力退化症，尤其年齡相關之肌力退化症。尤其，已發現該肌肉生長抑制素或活化素拮抗劑比麥盧單抗(bimagrumab)在為患有肌力退化症之老年人增加骨胳肌強度及功能方面具有治療效益。