AS REPRESENTED BY THE SECRETARY;THE GOVERNMENT OF THE UNITED STATES OF AMERICA; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
ANDERSON, LARRY J.,HAYNES, LIA M.,TRIPP, RALPH A.
申请号:
EP10807108
公开号:
EP2461825A4
申请日:
2010.08.04
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Immunogenic polypeptides corresponding to one or more RSV G glycoproteins, or analogues thereof, are provided as components of vaccines. The inventive compositions are useful as both a prophylactic and therapeutic for the prevention and treatment of RSV infections and associated pulmonary or other diseases. The inventive immunogens include regions of the RSV G protein, specifically, amino acid residues 164-176 of RSV G A2 protein or analogues thereof. This inventive immunogen is operable alone or in combination with other polypeptides such as the RSV G protein amino acid residues 155-206, or other vaccines such as live RSV vaccines, or inactivated RSV vaccines or immunogenic analogues thereof.