Ganymed Pharmaceuticals GmbH;TRON- Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Univers
发明人:
Ugur Sahin,Ozlem Tureci,Korden Walter,Maria Kreuzberg,Rita Mitnacht-Kraus,Fabrice Le Gall,Stefan Jacobs
申请号:
US15565848
公开号:
US20180117174A1
申请日:
2016.04.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides anti-CLDN18.2 antibody-drug conjugates which are effective for treating and/or preventing cancer diseases associated with cells expressing CLDN18.2, including gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.