#$%^&*AU2014246609A120141030.pdf#####H: rec tevven NRPo,,H] DCC REC 6865810_1docx:-9/]{/20ll ABSTRACT Disclosed are compounds having the formula: R2 R3 A Z 4 L-R4 1 2 3 wherein X 1, X2 , X3, R', R2, R , R4 , Y, A, Z, L and n are as defined herein, and methods of making and using the same.