USE OF ADENOSINE RECEPTOR SIGNALING TO MODULATE PERMEABILITY OF BLOOD-BRAIN BARRIER

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专利权人:

Margaret S. Bynoe

发明人:

Margaret S. Bynoe

申请号：

US13823266

公开号：

US20130224110A1

申请日:

2011.09.16

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to a method of increasing blood brain barrier (“BBB”) permeability in a subject. This method involves administering to the subject an agent or agents which activate both of the A1 and A2A adenosine receptors. Also disclosed is a method to decrease BBB permeability in a subject. This method includes administering to the subject an agent which inhibits or blocks the A2A adenosine receptor signaling. Compositions relating to the same are also disclosed.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/