Christopher J. Ong;Martin E. Gleave;Norihiro Hayashi;James Peacock
发明人:
Christopher J. Ong,Martin E. Gleave,Norihiro Hayashi,James Peacock
申请号:
US13262196
公开号:
US08808693B2
申请日:
2010.04.01
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Provided are methods, uses and pharmaceutical compositions for treatment of prostate cancer with a SEMA3C inhibitor in a biologically effective amount sufficient to cause cell death of a prostate cancer cell or to inhibit proliferation of the prostate cancer cells. The prostate cancer may be an androgen receptor (AR) positive prostate cancer and the SEMA3C inhibitor may be selected from one or more of the following: an antibody, a SEMA3C peptide, an antisense RNA, a siRNA, a shRNA or a small molecule.