Duffy, Joseph L.,Bao, Jianming,Ondeyka, Debra L.,Tyagarajan, Sriram,Shao, Patrick,Ye, Feng,Katipally, Revathi,Finke, Paul E.,Zang, Yi,Plotkin, Michael A.,Romero, F. Anthony,Moningka, Remond,Hussain, Z
申请号:
AU2011256444
公开号:
AU2011256444B2
申请日:
2011.05.13
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.