The present invention relates to a mixture powder of Platycodon grandiflorus and Momordica charantia, a capsule therefor, and a preparation method therefor and, specifically, dried powders of Platycodon grandiflorus and Momordica charantia including leaves, stems and roots are mixed in order to prevent and treat various respiratory diseases and adult diseases caused by a blood circulation disorder. According to the present invention, the Platycodon grandiflorus and Momordica charantia mixture powder preparation method comprises: a washing step (S10) of collecting and washing an at least 1-year-old Platycodon grandiflorus and Momordica charantia including leaves, stems and roots； a cutting step (S20) of respectively cutting the collected Platycodon grandiflorus and Momordica charantia at a predetermined length； a drying step (S30) of hot-air drying Platycodon grandiflorus and Momordica charantia in a dryer at a temperature higher than the boiling point of hydrocyanic acid gas； a pulverization step (S40) of preparing a Platycodon grandiflorus powder and a Momordica charantia powder by respectively pulverizing the dried Platycodon grandiflorus and Momordica charantia； and a mixing step (S50) of generating a mixture powder by mixing the Platycodon grandiflorus powder and the Momordica charantia powder in a mixing ratio of 1:0.5 to 1:2 by wt%. The present invention: has no side effects in the human body by using, as a basis, pure natural medicinal herbs in a natural state without separate artificial additives； can be effectively used for alleviating, preventing, and treating symptoms even with a relatively small amount because of mutual synergism； and is transparently encapsulated with an animal natural gelatin to be used as a heamatic medicine in Oriental medicine, thereby enabling long-term storage thereof, enabling abnormalities of contents to be checked by being conveniently portable anywhere and anytime, enabling convenient administration thereof, and having a low c
