(R) 7 kuroro N (kinukurijin 3 iru) benzo [b] thiophene 2 karubokisamido or the fact that the salt, and the acetylcholine esterase inhibiter which on the medicine manufacture it can allow are prescribed to the patient is included, the method acknowledgment performance being improved is stated, with the composition which it is related.< Selective figure >Figure 1(R)-7-クロロ-N-(キヌクリジン-3-イル)ベンゾ[b]チオフェン-2-カルボキサミド又はその製薬上許容しうる塩、及びアセチルコリンエステラーゼ阻害剤を患者に投与することを含む、認知機能を改善する方法が、関連する組成物と共に記載される。【選択図】図1