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COMPOSTO DE AZOL
专利权人:
ASTELLAS PHARMA INC.
发明人:
TAKASHI SUGANE,SATOSHI AOKI,RYOSUKE MUNAKATA,NORIYUKI KAWANO,KIYOHIRO SAMIZU,HIROMASA OKA,TAKAHIRO ISHII
申请号:
PT09797891
公开号:
PT2308869E
申请日:
2009.07.13
申请国别(地区):
PT
年份:
2012
代理人:
摘要:
[Problems] A compound which is useful as an active ingredient of a pharmaceutical composition for treating neuropathic pain is provided. [Means for Solution] The present inventors have made extensive studies on compounds having an FAAH inhibitory activity, and as a result, have found that an azole compound substituted with an N-(pyridin-3-yl)oxycarbonyl-piperidin-4-yl group and a phenyl group or a pharmaceutically acceptable salt thereof has an excellent FAAH inhibitory activity, thereby completing the present invention. The compound of the present invention is confirmed to have an excellent FAAH inhibitory activity and an antiallodynic effect in rat models with neuropathic pain, and thus is useful as an agent for preventing and/or an agent for treating neuropathic pain.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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