Institute For Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center
发明人:
Jonathan Chernoff,Hoi Yee Chow
申请号:
US16775747
公开号:
US20200239907A1
申请日:
2020.01.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Mice comprising a modified p21-activated kinase (Pak) inhibitor domain (PID*), optionally linked with GST and capable of constitutive expression of PID are provided. Also provided are cells, tissue, and organs obtainable from such mice, and methods for producing mice comprising a modified p21-activated kinase (Pak) inhibitor domain (PID*).