Jennifer M. Knipe,Laura E. Strong,Nicholas A. Peppas
申请号：
US14994704
公开号：
US09937256B2
申请日:
2016.01.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
In some aspects, methacrylate co-polymers crosslinked with an enzymatically cleavable peptide linker are provided and may be used for the oral delivery of a therapeutic. The peptide linker may be cleavable by an enzyme in the small intestine and may allow for the delivery of a therapeutic protein or nucleic acid to the small intestine. Also provided are methods of using the polymers for the treatment of a disease.
