Curcumin compositions herein are described for improving muscle performance, endurance capacity and resistance to fatigue, when administered in effective amounts to a subject in need of such improvement. The compositions are comprised of curcumin and at least one pharmaceutically and/or nutraceutically acceptable excipient such as a hydrophilic carrier and exhibit enhanced bioavailability. More particularly methods are described and include use of curcumin compositions to increase exercise time, performance and capacity and to prevent muscle soreness, fatigue and injury. The compositions enhance mitochondrial biogenesis by modulating mitochondrial function, increasing mitochondrial mass and oxygen consumption, thus increasing mitochondrial aerobic capacity. The compositions reduce oxidative muscle stress, by decreasing inflammatory cytokines and inflammatory markers. Curcumin compositions are safe for consumption for pharmaceutical and/or nutraceutical purposes and are prepared by economic methods using conventional equipments and can be effectively used for enhancing muscle and exercise performance.L'invention concerne des compositions à base de curcumine destinées à améliorer les performances musculaires, les capacités d'endurance et la résistance à la fatigue, lorsqu'elles sont administrées en quantités efficaces à un sujet nécessitant une telle amélioration. Lesdites compositions comprennent de la curcumine et au moins un excipient acceptable sur le plan pharmaceutique et/ou nutraceutique tel qu'un transporteur hydrophile et présentent une biodisponibilité améliorée. Plus particulièrement, l'invention concerne des méthodes consistant à utiliser lesdites compositions à base de curcumine pour augmenter le temps d'exercice, les performances et les capacités et prévenir les courbatures, la fatigue et les blessures. Lesdites compositions améliorent la biogenèse mitochondriale par la modulation de la fonction mitochondriale, l'augmentation de la masse mitochondriale e
