THE GOVERNMENT OF THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
MOSS, BERNARD,WYATT, LINDA,EARL, PATRICIA
申请号:
ES07874019
公开号:
ES2396376T3
申请日:
2007.08.24
申请国别(地区):
ES
年份:
2013
代理人:
摘要:
A recombinant modified vaccinia virus Ankara (MVA) comprising a heterologous DNA sequence inserted into an intergenic region (IGR) the MVA genome, which is located between or flanked by the open reading frames (ORFs) of 069 to 070 MVA genome nomenclature CDC / Acambis, it is corresponding to ORFs I8R-G1L nomenclature Copenhagen.Un virus vaccinia Ankara modificado (MVA) recombinante que comprende una secuencia de DNA heteróloga insertada en una región intergénica (IGR) del genoma del MVA, que está localizado entre, o flanqueado por, los marcos de lectura abiertos (ORFs) 069-070 del genoma del MVA en la nomenclatura de CDC/Acambis, que corresponde a los ORFs I8R-G1L en la nomenclatura de Copenhague.